Prof. Jeffrey M. Hausdorff

Prof. Jeffrey M. Hausdorff

Medicine

Research work

Prof. Hausdorff received undergraduate and graduate degrees from The Cooper Union, MIT, and Boston University in biomechanics and biomedical engineering. After completing postdoctoral training in gerontology at Harvard Medical School, he joined the faculty there, first as an instructor and later as an assistant professor.  For the past 24 years, he has been directing a research center that studies gait, cognition, and mobility at the Tel Aviv Sourasky Medical Center. Since 2002, he has also been a professor in the Department of Physical Therapy in the Faculty of Medical & Health Sciences at Tel Aviv University.

Prof. Hausdorff has authored more than 400 peer-reviewed publications, has an H-index of > 130, and his work has been cited more than 95,000 times. His research has been funded by the NIH, the ISF, the European Commission, the Israel Ministry of Science, the Michael J Fox Foundation for Parkinson’s Disease, and other private agencies and has been widely recognized.

Prof. Hausdorff and the research team that he leads aim to better understand, evaluate, treat, and prevent deficits in gait, balance, and cognitive function associated with aging and neurological disease. They study gait, motor control, and brain function, with a special focus on motor-cognitive interactions, gait variability, “fractal” physiology, falls in older adults, and freezing of gait. His research on the dependence of everyday walking on specific cognitive abilities led to important new insights about fall risk and paved the way for new therapeutic approaches such as VR-based interventions and the use of non-invasive brain stimulation to improve mobility and reduce fall risk. Innovative studies quantifying real-world mobility set the stage for a new way of evaluating gait and fall risk during daily living using digital outcomes, machine learning, and wearable sensors. In the long run, Prof. Hausdorff seeks to build on these research findings to improve the health-related quality of life of older adults and people with neurological disease.

 

Professional Experience and Academic Appointments (selected)

2014 –    Present                  Director, Center for the Study of Movement, Cognition, and Mobility,Tel Aviv Medical Center

2012 – present                     Full Professor, Sagol School of Neuroscience, Tel Aviv University

2011 – present                      Full Professor, Faculty of Medical & Health Sciences, Tel Aviv University

2006 – 2011                          Associate Professor, Department of Physical Therapy. Faculty of Medical and Health Sciences  

2002 – 2006                         Senior Lecturer, Department of Physical Therapy, Faculty of Medical and Health Sciences  

2002 – 2014                         Lecturer in Medicine, Harvard Medical School

2000 – 2014                         Director, Laboratory for Gait Analysis and Neurodynamics, Tel Aviv Medical Center

1999 – 2002                         Associate Director, Institute for Nonlinear Dynamics in Physiology and Medicine

1999 – 2002                         Assistant Professor of Medicine, Harvard Medical School

1997 – 2002                         Research Affiliate, MIT

1996 – 1997                         NRSA Fellow, Harvard Medical School

1995 – 1998                         Instructor in Medicine, Harvard Medical School

1990 – 1995                         Biomedical Scientist, Harvard Medical School

1986 – 1988                         Research Associate, MIT Newman Biomechanics Laboratory

 

Selected Other Appointments

2024 – Present                     Board member, International Consortium on Freezing of Gait (ICFOG)

2021                                     Scientific Committee Chair, International Conference on Ambulatory Monitoring of Physical Activity and Movement (ICAMPAM)

2022                                     Scientific Committee Chair, International Conference on Ambulatory Monitoring of Physical Activity and Movement (ICAMPAM)

2021 – present                     Task Force Global Guidelines for Falls in Older Adults (and working group leader falls and technology)

2021 – present                     Scientific Advisory Board, Tel Aviv University Healthy Longevity Research Center

2016 – present                     Gait Advisory Committee for the Michael J. Fox Foundation

2015 – present                     Movement Disorders Society Task Force on Technology

2014 – present                     Board of Directors, International Society for the Measurement of Physical Behaviour

2012 – 2016                         Board of Directors, International Society of Postural and Gait Research

2012  – 2014                        Organizing Committee, Gerontological Society of America and NIA sponsored 3-year conference workshop series, "Aging, the CNS, and Mobility”

2009                                     International Organizing Committee, International Society of Posture & Gait Research

2006, 2008, 2010                 Organizing committee, International Conference on Gait and Mental Function

2003 – 2015                         American Federation of Aging Research's National Scientific Advisory Council

 

Current Editorial Positions

Associate Editor                                   Journal of Gerontology Medical Sciences

Associate Editor                                   Journal of Neural Engineering and Rehabilitation

Editorial board                                     Gait and Posture

 

Honors and Awards (selected)

 

2013                       Recipient of the Gerontology Society of America’s Excellence in Rehabilitation of Aging Persons Award

2014                       Nefesh B’Nefesh Bonei Zion Prize in Medicine and Science

2014                       Paper listed among the top 5 most cited papers in the history of rehabilitation

2016                       Named Fellow of the Gerontological Society of America

2019                       Listed among the top 0.01% of scientists based on impact of publications (from 1960-2017; see Ioannidis et al., 2019)

2020                       Listed among scientists for career-long citation impact up until the end of 2019 and for citation impact during the single calendar year 2019 (ranked 17th and 6th, respectively, among all scientists in Israel)  (see Ioannidis et al., 2020)

2021, 2022            Listed among the top 0.01% of scientists based on impact of publications  (see Ioannidis et al.)

2022                      Listed among the top 1,000 “Best Scientists in the World” https://research.com/scientists-rankings/best-scientists.

2023                      Aufzien Family Center for the Prevention and Treatment of Parkinson's Disease APPD Established Scientist Prize 2023

2024                      Igor Orenstein Chair for the Study of Geriatrics

 

Link to PubMed Publications

https://pubmed.ncbi.nlm.nih.gov/?term=hausdorff+jm+%5Bau%5D&sort=date

 

Link to CV

https://drive.google.com/file/d/1DYg6LNqSI5GfT4FYDoWTnmYI8bSMxF5t/view?usp=sharing

Areas of interest & scientific knowledge

Medicine

  • Neuroscience
  • Rehabilition, Physical Therapy
  • Signal processing, machine learning and biomedical engineering
  • Gait, Falls And Cognition In Older Adults
Selected Publications
  • Montero-Odasso M, van d, V, Martin FC, Petrovic M, Tan MP, Ryg J, Aguilar-Navarro S, Alexander NB, Becker C, Blain H, Bourke R, Cameron ID, Camicioli R, Clemson L, Close J, Delbaere K, Duan L, Duque G, Dyer SM, Freiberger E, Ganz DA, Gomez F, Hausdorff JM, Hogan DB, Hunter SMW, Jauregui JR, Kamkar N, Kenny RA, Lamb SE, Latham NK, Lipsitz LA, Liu-Ambrose T, Logan P, Lord SR, Mallet L, Marsh D, Milisen K, Moctezuma-Gallegos R, Morris ME, Nieuwboer A, Perracini MR, Pieruccini-Faria F, Pighills A, Said C, Sejdic E, Sherrington C, Skelton DA, Dsouza S, Speechley M, Stark S, Todd C, Troen BR, van der Cammen T, Verghese J, Vlaeyen E, Watt JA, Masud T. World guidelines for falls prevention and management for older adults: a global initiative. Age Ageing 2022;51.
  • Denk D, Herman T, Zoetewei D, Ginis P, Brozgol M, Cornejo TP, Decaluwe E, Ganz N, Palmerini L, Giladi N, Nieuwboer A, Hausdorff JM. Daily-Living Freezing of Gait as Quantified Using Wearables in People With Parkinson Disease: Comparison With Self-Report and Provocation Tests. Phys Ther 2022;102.
  • Droby A, Varangis E, Habeck C, Hausdorff JM, Stern Y, Mirelman A, Maidan I. Effects of aging on cognitive and brain inter-network integration patterns underlying usual and dual-task gait performance. Front Aging Neurosci 2022;14:956744.
  • Galperin I, Mirelman A, Schmitz-Hubsch T, Hsieh KL, Regev K, Karni A, Brozgol M, Cornejo TP, Lynch SG, Paul F, Devos H, Sosnoff J, Hausdorff JM. Treadmill training with virtual reality to enhance gait and cognitive function among people with multiple sclerosis: a randomized controlled trial. J Neurol 2023;270:1388-1401.
  • Kahya M, Gouskova NA, Lo OY, Zhou J, Cappon D, Finnerty E, Pascual-Leone A, Lipsitz LA, Hausdorff JM, Manor B. Brain activity during dual-task standing in older adults. J Neuroeng Rehabil 2022;19:123.
  • Ding H, Droby A, Anwar AR, Bange M, Hausdorff JM, Nasseroleslami B, Mirelman A, Maidan I, Groppa S, Muthuraman M. Treadmill training in Parkinson's disease is underpinned by the interregional connectivity in cortical-subcortical network. NPJ Parkinsons Dis 2022;8:153.
  • Molad J, Hallevi H, Seyman E, Rotschild O, Bornstein NM, Tene O, Giladi N, Hausdorff JM, Mirelman A, Ben AE. CCR5-Delta32 polymorphism-a possible protective factor from gait impairment amongst post-stroke patients. Eur J Neurol 2023;30:692-701.
  • Sayig-Keren RM, Dagan M, Cornejo TP, Brozgol M, Gazit E, Manor B, Hausdorff JM. The Potential of Transcranial Alternating Current Stimulation to Alleviate Dual-Task Gait Costs in Older Adults: Insights from a Double-Blinded Pilot Study. Gerontology 2023;69:513-518.
  • Ghosal R, Varma VR, Volfson D, Hillel I, Urbanek J, Hausdorff JM, Watts A, Zipunnikov V. Distributional data analysis via quantile functions and its application to modeling digital biomarkers of gait in Alzheimer's Disease. Biostatistics 2023;24:539-561.
  • Keogh A, Alcock L, Brown P, Buckley E, Brozgol M, Gazit E, Hansen C, Scott K, Schwickert L, Becker C, Hausdorff JM, Maetzler W, Rochester L, Sharrack B, Vogiatzis I, Yarnall A, Mazza C, Caulfield B. Acceptability of wearable devices for measuring mobility remotely: Observations from the Mobilise-D technical validation study. Digit Health 2023;9:20552076221150745.
  • Kozlovski T, Hausdorff JM, Davidov O, Giladi N, Mirelman A, Benjamini Y. A novel performance scoring quantification framework for stress test set-ups. PLoS One 2023;18:e0284083.
  • Buchman AS, Wang T, Oveisgharan S, Zammit AR, Yu L, Li P, Hu K, Hausdorff JM, Lim ASP, Bennett DA. Correlates of Person-Specific Rates of Change in Sensor-Derived Physical Activity Metrics of Daily Living in the Rush Memory and Aging Project. Sensors (Basel) 2023;23.
  • Salis F, Bertuletti S, Bonci T, Caruso M, Scott K, Alcock L, Buckley E, Gazit E, Hansen C, Schwickert L, Aminian K, Becker C, Brown P, Carsin AE, Caulfield B, Chiari L, D'Ascanio I, Del DS, Eskofier BM, Garcia-Aymerich J, Hausdorff JM, Hume EC, Kirk C, Kluge F, Koch S, Kuederle A, Maetzler W, Mico-Amigo EM, Mueller A, Neatrour I, Paraschiv-Ionescu A, Palmerini L, Yarnall AJ, Rochester L, Sharrack B, Singleton D, Vereijken B, Vogiatzis I, Della CU, Mazza C, Cereatti A, For The Mobilise-. A multi-sensor wearable system for the assessment of diseased gait in real-world conditions. Front Bioeng Biotechnol 2023;11:1143248.
  • Zanotto T, Galperin I, Mirelman A, Chen L, Regev K, Karni A, Schmitz-Hubsch T, Paul F, Lynch SG, Akinwuntan AE, Devos H, Hausdorff JM, Sosnoff JJ. Association Between Frailty and Free-Living Walking Performance in People With Multiple Sclerosis. Phys Ther 2023;103.
  • Mico-Amigo ME, Bonci T, Paraschiv-Ionescu A, Ullrich M, Kirk C, Soltani A, Kuderle A, Gazit E, Salis F, Alcock L, Aminian K, Becker C, Bertuletti S, Brown P, Buckley E, Cantu A, Carsin AE, Caruso M, Caulfield B, Cereatti A, Chiari L, D'Ascanio I, Eskofier B, Fernstad S, Froehlich M, Garcia-Aymerich J, Hansen C, Hausdorff JM, Hiden H, Hume E, Keogh A, Kluge F, Koch S, Maetzler W, Megaritis D, Mueller A, Niessen M, Palmerini L, Schwickert L, Scott K, Sharrack B, Sillen H, Singleton D, Vereijken B, Vogiatzis I, Yarnall AJ, Rochester L, Mazza C, Del DS. Assessing real-world gait with digital technology? Validation, insights and recommendations from the Mobilise-D consortium. J Neuroeng Rehabil 2023;20:78.
  • Dubbioso R, Spisto M, Hausdorff JM, Aceto G, Iuzzolino VV, Senerchia G, De MS, Marcuccio L, Femiano C, Iodice R, Salvatore E, Santangelo G, Trojano L, Moretta P. Cognitive impairment is associated with gait variability and fall risk in amyotrophic lateral sclerosis. Eur J Neurol 2023;30:3056-3067.
  • Ding H, Droby A, Anwar AR, Hausdorff JM, Nasseroleslami B, Mirelman A, Maidan I, Muthuraman M. Treadmill training in Parkinson's disease: possible role of prefrontal modifications in the improved cortical-subcortical network function. Neural Regen Res 2024;19:407-408.
  • Burton W, Ma Y, Manor B, Hausdorff JM, Kowalski MH, Bain PA, Wayne PM. The impact of neck pain on gait health: a systematic review and meta-analysis. BMC Musculoskelet Disord 2023;24:618.
  • Cappon D, den BT, Yu W, LaGanke N, Fox R, Brozgol M, Hausdorff JM, Manor B, Pascual-Leone A. An Educational Program for Remote Training and Supervision of Home-Based Transcranial Electrical Stimulation: Feasibility and Preliminary Effectiveness. Neuromodulation 2024;27:636-644.
  • Camicioli R, Morris ME, Pieruccini-Faria F, Montero-Odasso M, Son S, Buzaglo D, Hausdorff JM, Nieuwboer A. Prevention of Falls in Parkinson's Disease: Guidelines and Gaps. Mov Disord Clin Pract 2023;10:1459-1469.
  • Ma Y, Gow BJ, Song R, Rist PM, Hausdorff JM, Lipsitz LA, Manor B, Wayne PM. Long-term Tai Chi practice in older adults is associated with "younger" functional abilities. Aging Cell 2024;23:e14023.
  • Herman T, Barer Y, Bitan M, Sobol S, Giladi N, Hausdorff JM. A meta-analysis identifies factors predicting the future development of freezing of gait in Parkinson's disease. NPJ Parkinsons Dis 2023;9:158.
  • Mirelman A, Volkov J, Salomon A, Gazit E, Nieuwboer A, Rochester L, Del DS, Avanzino L, Pelosin E, Bloem BR, Della CU, Cereatti A, Thaler A, Roggen D, Mazza C, Shirvan J, Cedarbaum JM, Giladi N, Hausdorff JM. Digital Mobility Measures: A Window into Real-World Severity and Progression of Parkinson's Disease. Mov Disord 2024;39:328-338.
  • Zoetewei D, Herman T, Ginis P, Palmerini L, Brozgol M, Thumm PC, Ferrari A, Ceulemans E, Decaluwe E, Hausdorff JM, Nieuwboer A. On-Demand Cueing for Freezing of Gait in Parkinson's Disease: A Randomized Controlled Trial. Mov Disord 2024;39:876-886.
  • Bacon KL, Felson DT, Jafarzadeh SR, Kolachalama VB, Hausdorff JM, Gazit E, Stefanik JJ, Corrigan P, Segal NA, Lewis CE, Nevitt MC, Kumar D. Gait Alterations and Association With Worsening Knee Pain and Physical Function: A Machine Learning Approach With Wearable Sensors in the Multicenter Osteoarthritis Study. Arthritis Care Res (Hoboken ) 2024;76:984-992.
  • Brand YE, Kluge F, Palmerini L, Paraschiv-Ionescu A, Becker C, Cereatti A, Maetzler W, Sharrack B, Vereijken B, Yarnall AJ, Rochester L, Del DS, Muller A, Buchman AS, Hausdorff JM, Perlman O. Automated Gait Detection in Older Adults during Daily-Living using Self-Supervised Learning of Wrist-Worn Accelerometer Data: Development and Validation of ElderNet. Res Sq  2024.
  • Kluge F, Brand YE, Mico-Amigo ME, Bertuletti S, D'Ascanio I, Gazit E, Bonci T, Kirk C, Kuderle A, Palmerini L, Paraschiv-Ionescu A, Salis F, Soltani A, Ullrich M, Alcock L, Aminian K, Becker C, Brown P, Buekers J, Carsin AE, Caruso M, Caulfield B, Cereatti A, Chiari L, Echevarria C, Eskofier B, Evers J, Garcia-Aymerich J, Hache T, Hansen C, Hausdorff JM, Hiden H, Hume E, Keogh A, Koch S, Maetzler W, Megaritis D, Niessen M, Perlman O, Schwickert L, Scott K, Sharrack B, Singleton D, Vereijken B, Vogiatzis I, Yarnall A, Rochester L, Mazza C, Del DS, Mueller A. Real-World Gait Detection Using a Wrist-Worn Inertial Sensor: Validation Study. JMIR Form Res 2024;8:e50035.
  • Galperin I, Buzaglo D, Gazit E, Shimoni N, Tamir R, Regev K, Karni A, Hausdorff JM. Gait and heart rate: do they measure trait or state physical fatigue in people with multiple sclerosis? J Neurol 2024;271:4462-4472.
  • Zadka A, Rabin N, Gazit E, Mirelman A, Nieuwboer A, Rochester L, Del DS, Pelosin E, Avanzino L, Bloem BR, Della CU, Cereatti A, Hausdorff JM. A wearable sensor and machine learning estimate step length in older adults and patients with neurological disorders. NPJ Digit Med 2024;7:142.
  • Salomon A, Gazit E, Ginis P, Urazalinov B, Takoi H, Yamaguchi T, Goda S, Lander D, Lacombe J, Sinha AK, Nieuwboer A, Kirsch LC, Holbrook R, Manor B, Hausdorff JM. A machine learning contest enhances automated freezing of gait detection and reveals time-of-day effects. Nat Commun 2024;15:4853.
  • Zoetewei D, Ginis P, Goris M, Gilat M, Herman T, Brozgol M, Thumm PC, Hausdorff JM, Nieuwboer A, D'Cruz N. Which Gait Tasks Produce Reliable Outcome Measures of Freezing of Gait in Parkinson's Disease? J Parkinsons Dis 2024;14:1163-1174.
  • Oveisgharan S, Wang T, Hausdorff JM, Bennett DA, Buchman AS. Motor and Nonmotor Measures and Declining Daily Physical Activity in Older Adults. JAMA Netw Open 2024;7:e2432033.
  • Brand YE, Kluge F, Palmerini L, Paraschiv-Ionescu A, Becker C, Cereatti A, Maetzler W, Sharrack B, Vereijken B, Yarnall AJ, Rochester L, Del DS, Muller A, Buchman AS, Hausdorff JM, Perlman O. Self-supervised learning of wrist-worn daily living accelerometer data improves the automated detection of gait in older adults. Sci Rep 2024;14:20854.
  • Wang H, Ullah Z, Gazit E, Brozgol M, Tan T, Hausdorff JM, Shull PB, Ponger P. Step Width Estimation in Individuals With and Without Neurodegenerative Disease Via a Novel Data-Augmentation Deep Learning Model and Minimal Wearable Inertial Sensors. IEEE J Biomed Health Inform 2024;PP.
  • Lange-Maia B, Wang T, Oveisgharan S, Hausdorff JM, Bennett DA, Buchman AS. Mobility abilities mediate the association of a more active lifestyle with mobility disability in older adults. J Gerontol A Biol Sci Med Sci 2024.
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